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What is a Vaccine

Vaccines are like practice runs for the immune system—teaching the body to fight germs before they can cause serious disease.

hand with glove on using vaccine

Susanne Tanski, MD, MPH, Pediatrics

  • Vaccines act as training exercises for the immune system, helping the body recognize and respond to germs more effectively before serious illness develops.
  • They may include fragments, dead, or weakened forms of germs to safely prepare the immune system.
  • Some vaccines prevent symptoms altogether, while others make infections much milder if exposure occurs.
  • Common mild side effects include a sore arm or brief fever, but vaccines prevent serious outcomes like pneumonia, disability, birth defects, and cancer.
  • Immunity from vaccines often requires multiple doses or boosters, unlike natural infections that may trigger immunity after one exposure but at higher health risks.
  • Annual vaccines, such as flu and COVID, are needed because respiratory viruses change frequently.
  • Staying up to date with the AAP-recommended vaccine schedule ensures protection during the periods of highest risk for each illness.
  • Examples include RSV, where the first infection season is most severe, rotavirus, which primarily threatens infants, and Hib, which affects mainly young children.
  • Following the full vaccine schedule supports lifelong health and disease prevention for children.

Learn more about vaccines for children
 


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